Analysis of dose/time/response relationships for chronic toxic effects: the case of acrylamide.

Abstract

This case study illustrates how a very simple dynamic modeling approach can extract information of interest for both toxic mechanism research and risk assessment from a series of dose/time/response data. The technique is applicable for effects that are thought to result from damage processes that are reversible, at least at low doses and times of exposure… (More)

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Cite this paper

@article{Hattis1990AnalysisOD, title={Analysis of dose/time/response relationships for chronic toxic effects: the case of acrylamide.}, author={Dale B. Hattis and Karen Shapiro}, journal={Neurotoxicology}, year={1990}, volume={11 2}, pages={219-36} }