Analysis of dose response for circulatory disease after radiotherapy for benign disease.

@article{Little2012AnalysisOD,
  title={Analysis of dose response for circulatory disease after radiotherapy for benign disease.},
  author={Mark P. Little and Ruth A. Kleinerman and Marilyn S. Stovall and Susan A. Smith and Kiyohiko Mabuchi},
  journal={International journal of radiation oncology, biology, physics},
  year={2012},
  volume={84 5},
  pages={1101-9}
}
PURPOSE To assess the shape of the dose-response for various circulatory disease endpoints, and modifiers by age and time since exposure. METHODS AND MATERIALS This was an analysis of the US peptic ulcer data testing for heterogeneity of radiogenic risk by circulatory disease endpoint (ischemic heart, cerebrovascular, other circulatory disease). RESULTS There were significant excess risks for all circulatory disease, with an excess relative risk Gy(-1) of 0.082 (95% CI 0.031-0.140), and… CONTINUE READING