Analysis of dopamine D1 and D2 receptor involvement in d- and l-amphetamine-induced anorexia in rats.

@article{Gilbert1985AnalysisOD,
  title={Analysis of dopamine D1 and D2 receptor involvement in d- and l-amphetamine-induced anorexia in rats.},
  author={David B. Gilbert and S J Cooper},
  journal={Brain research bulletin},
  year={1985},
  volume={15 4},
  pages={385-9}
}
The concept of dopamine receptor subtypes and the recent development of selective dopamine receptor agonists and antagonists raises the possibility of specific subtype involvement in amphetamine-induced anorexia, and, furthermore, provides the means to evaluate the possibility. Using a test of palatable food consumption by nondeprived male rats, our data confirmed a more potent suppressant effect of d-amphetamine on food intake, compared to l-amphetamine (potency ratio 5.32:1). The test proved… CONTINUE READING

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