Analysis of discrimination mechanisms in the mammalian olfactory system using a model nose

@article{Persaud1982AnalysisOD,
  title={Analysis of discrimination mechanisms in the mammalian olfactory system using a model nose},
  author={Krishna C. Persaud and George H. Dodd},
  journal={Nature},
  year={1982},
  volume={299},
  pages={352-355}
}
Olfaction exhibits both high sensitivity for odours and high discrimination between them1. We suggest that to make fine discriminations between complex odorant mixtures containing varying ratios of odorants without the necessity for highly specialized peripheral receptors, the olfactory systems makes use of feature detection using broadly tuned receptor cells organized in a convergent neurone pathway. As a test of this hypothesis we have constructed an electronic nose using semiconductor… 

Representation of Odor Information in the Olfactory System: From Biology to an Artificial Nose

TLDR
This paper describes how physiological aspects of the processes that underlie how odors are encoded at each level in the olfactory pathway in the brain are characterized in biological experiments, captured in a computational model, and then used to design and build a biologically inspired artificial device.

Artificial noses.

TLDR
The most commonly employed sensor types in artificial noses: electrical, gravimetric, and optical sensors are highlighted, covering areas such as food and beverage quality control, chemical warfare agent detection, and medical diagnostics.

Testing olfactory models with an artificial experimental platform

Artificial olfaction systems have been investigated since more than two decades on alleged property of similarities between the receptive field of natural receptors and artificial sensors. Due to the

Principles of odor coding in vertebrates and artificial chemosensory systems.

TLDR
An up-to-date overview of the current knowledge of both fields is provided and it is hoped this review will be a breeding ground for better information, communication, and data exchange between very related but so far little connected fields.

An odor discrimination model with application to kin recognition in social insects.

TLDR
A model for the process of odor discrimination is presented, which hypothesizes neural processing capabilities that include the logarithmic transformations of electrical potentials to generate a scalar quantity representing the "similarity" of two multivalued signals and quantifies the notion of phenotype matching.

An olfactory neuronal network for vapor recognition in an artificial nose

TLDR
A biologically based neuronal network based directly on neural circuits of the vertebrate olfactory system is implemented in an artificial chemosensing system, enabling discrimination among organic vapors over a range of input signal intensities.

Odor Discrimination Using Cell-Based Odor Biosensor System With Fluorescent Image Processing

TLDR
Odorants were discriminated using an odor biosensor system with cells expressing different types of olfactory receptors to suggest that the combination of a biosensor and image processing technique has the potential to discriminate between different odorants even if the cells are placed at random.
...

References

SHOWING 1-10 OF 12 REFERENCES

AN ELECTRONIC ANALOG FOR THE OLFACTORY PROCESSES * †

TLDR
Any attempt to devise a qualitative and quantitative analog for the receptor surface can at this time be approached only by constructing detector mechanisms which display differential adsorption properties for various odorant compounds or detectors which depend on some physical chemical change at the detector surface which can be translated into an electrical signal.

A chemical-modification approach to the olfactory code. Studies with a thiol-specific reagent.

TLDR
The effects of thiol-specific reagents on the amplitude of the electro-olfactogram (E.O.G.G.) responses elicited from frog olfactory mucosa by pulses of odorant vapours was studied and it is suggested that theOlfactory code at this level of the Olfactory system may be elucidated by chemical-modification methods.

Polar vapour detector based on thermal modulation of contact potential

A sensitive, variable-temperature contact-potential device based on the Kelvin-Zisman method was constructed. Its use as a detector of polar vapours was demonstrated. Thermal pulsing of one plate of

The Determination of Phenolphthalein in Mineral Oil Emulsion

A volumetric method based on the iodination of phenolphthalein in an alkaline medium has been applied to the assay for that compound in emulsions. The emulsion is broken by the addition of an

InP-Langmuir-film m.i.s. structures

The electrical properties of m.i.s. structures based on InP and Langmuir films have been investigated. A strongly inverted low-frequency-type C/V response occurs at about 30 Hz. Surface-state

Models of the nervous system

Biochemical studies in olfaction.