Analysis of differentiation potentials and gene expression profiles of mesenchymal stem cells derived from periodontal ligament and Wharton's jelly of the umbilical cord.

@article{Yu2013AnalysisOD,
  title={Analysis of differentiation potentials and gene expression profiles of mesenchymal stem cells derived from periodontal ligament and Wharton's jelly of the umbilical cord.},
  author={Shi Yu and Jie Long and Jinhua Yu and Juan Du and Ping Ma and Yushi Ma and Dongmei Yang and Zhipeng Fan},
  journal={Cells, tissues, organs},
  year={2013},
  volume={197 3},
  pages={209-23}
}
PDLSC-mediated periodontal tissue regeneration is considered a promising method for periodontitis treatment, but the supply of PDLSCs is limited. As a potential alternative, WJCMSCs are readily available; however, there is a lack of evidence proving that WJCMSCs are suitable for periodontal tissue regeneration. In this study, we investigated the characteristics of WJCMSCs and PDLSCs. We found the osteo-/dentinogenic, adipogenic and chondrogenic differentiation potentials of PDLSCs were more… CONTINUE READING

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