Analysis of differential protein expression by cisplatin treatment in cervical carcinoma cells.

@article{Yim2006AnalysisOD,
  title={Analysis of differential protein expression by cisplatin treatment in cervical carcinoma cells.},
  author={E-K Yim and K Y Lee and C Kim and J Y Park},
  journal={International journal of gynecological cancer : official journal of the International Gynecological Cancer Society},
  year={2006},
  volume={16 2},
  pages={690-7}
}
Cisplatin (cis-diaminedichloroplatinum), a DNA-damaging agent, which readily induces apoptosis in vitro, is one of the widely used anticancer drug in the treatment of human malignancies. Cisplatin has played an important role in cervical cancer management for effective chemotherapeutic regimen, but the underlying mechanisms inducing cell death at protein level are unknown. Using proteome analysis, an investigation aimed at a better understanding of the antiproliferative mechanisms by cisplatin… CONTINUE READING
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