Analysis of differential PDT effect in rat bladder tumor models according to concentrations of intravesical hexyl-aminolevulinate.

Abstract

The hexylester of 5-aminolevulinic acid (HAL) is a very efficient precursor of the photosensitizer protoporphyrin IX (PpIX) for photodynamic therapy (PDT). Our previous study, performed in rat orthotopic bladder tumors, indicated an opposite effect of HAL/PpIX-PDT according to HAL concentration. The present study investigated possible reasons for this… (More)
DOI: 10.1039/b804921a

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@article{Berrahmoune2008AnalysisOD, title={Analysis of differential PDT effect in rat bladder tumor models according to concentrations of intravesical hexyl-aminolevulinate.}, author={Saoussen Berrahmoune and Nicolas Fotinos and Lina N Bezdetnaya and Norbert Lange and Jean Claude Guedenet and François Guillemin and Marie Ange D'hallewin}, journal={Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology}, year={2008}, volume={7 9}, pages={1018-24} }