Corpus ID: 12357076

Analysis of dietary fat, calories, body weight, and the development of mammary tumors in rats and mice: a review.

@article{Freedman1990AnalysisOD,
  title={Analysis of dietary fat, calories, body weight, and the development of mammary tumors in rats and mice: a review.},
  author={L. Freedman and C. Clifford and M. Messina},
  journal={Cancer research},
  year={1990},
  volume={50 18},
  pages={
          5710-9
        }
}
  • L. Freedman, C. Clifford, M. Messina
  • Published 1990
  • Medicine
  • Cancer research
  • We have extracted from the literature data from 100 animal experiments, involving 7838 rats and mice, which compared the effects of different levels of dietary fat and/or calorie intake on the development of mammary tumors. Both higher calorie intake (P less than 0.0001) and higher fat intake (P less than 0.0001) independently increased mammary tumor incidence in Sprague-Dawley rats and in mice, as judged from analyses combining ad libitum feeding experiments and restricted feeding experiments… CONTINUE READING
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