Corpus ID: 12357076

Analysis of dietary fat, calories, body weight, and the development of mammary tumors in rats and mice: a review.

  title={Analysis of dietary fat, calories, body weight, and the development of mammary tumors in rats and mice: a review.},
  author={L. Freedman and C. Clifford and M. Messina},
  journal={Cancer research},
  volume={50 18},
  • L. Freedman, C. Clifford, M. Messina
  • Published 1990
  • Medicine
  • Cancer research
  • We have extracted from the literature data from 100 animal experiments, involving 7838 rats and mice, which compared the effects of different levels of dietary fat and/or calorie intake on the development of mammary tumors. Both higher calorie intake (P less than 0.0001) and higher fat intake (P less than 0.0001) independently increased mammary tumor incidence in Sprague-Dawley rats and in mice, as judged from analyses combining ad libitum feeding experiments and restricted feeding experiments… CONTINUE READING
    240 Citations

    Figures, Tables, and Topics from this paper

    Dietary fat, body weight, and cancer: contributions of studies in rodents to understanding these cancer risk factors in humans.
    • 5
    • PDF
    Dietary fat, calories, and mammary gland tumorigenesis.
    • C. Welsch
    • Biology, Medicine
    • Advances in experimental medicine and biology
    • 1992
    • 32
    Diet and breast cancer: studies in laboratory animals.
    • 22
    • PDF


    Total calories, body weight, and tumor incidence in mice.
    • 225
    • Highly Influential
    • PDF
    Dietary cholesterol and experimental mammary cancer development.
    • 18
    Effects of dietary fat on age-dependent sensitivity to mammary carcinogenesis.
    • 20
    Effect of duration of high fat intake on enhancement of mammary carcinogenesis in rats.
    • T. Dao, P. Chan
    • Chemistry, Medicine
    • Journal of the National Cancer Institute
    • 1983
    • 50
    Enhancement of mammary carcinogenesis by a high-fat diet in Fischer, Long-Evans, and Sprague-Dawley rats.
    • 58
    • PDF
    Effects of different dietary fats on mammary carcinogenesis.
    • 90