Analysis of cyclodextrins using fast atom bombardment/mass spectrometry and tandem mass spectrometry

  title={Analysis of cyclodextrins using fast atom bombardment/mass spectrometry and tandem mass spectrometry},
  author={Robert D. Voyksner and Fred P. Williams and Cynthia S. Smith and D. L. Koble and Herbert H Seltzman},
  journal={Journal of Mass Spectrometry},
The combination of fast atom bombardment/mass spectrometry (FAB/MS) and FAB with tandem mass spectrometry (FAB/MS/MS) was used for the characterization of nearly 30 chemically modified cyclodextrins. Optimum FAB/MS analysis conditions as well as both positive and negative ion FAB data are presented. In addition, FAB/MS and FAB/MS/MS were used to characterize the in vitro reaction products of β-cyclodextrin (βCD) with soman, an organophosphorous nerve agent. The main product identified from the… 
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