Analysis of co-expression networks for circular RNAs and mRNAs reveals that circular RNAs hsa_circ_0047905, hsa_circ_0138960 and has-circRNA7690-15 are candidate oncogenes in gastric cancer.

@article{Lai2017AnalysisOC,
  title={Analysis of co-expression networks for circular RNAs and mRNAs reveals that circular RNAs hsa_circ_0047905, hsa_circ_0138960 and has-circRNA7690-15 are candidate oncogenes in gastric cancer.},
  author={Zhiyong Lai and Yang Yang and Yichao Yan and Tao Li and Yansen Li and Zhu Wang and Zhan-long Shen and Ying-jiang Ye and Kewei Jiang and Shan Wang},
  journal={Cell cycle},
  year={2017},
  volume={16 23},
  pages={
          2301-2311
        }
}
Accumulating evidence has suggested that circular RNAs (circRNAs) play important roles in oncogenesis and tumor progression. However, our knowledge of circRNAs in gastric cancer (GC) remains limited. To investigate circRNAs involved in GC oncogenesis, we examined differentially-expressed circRNAs and mRNAs in GC tissues and paired noncancerous mucosa tissues using circRNA and mRNA microarrays. Next, we built gene co-expression networks according to the degree of correlation to predict the… CONTINUE READING
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