Analysis of cerebrospinal fluid and cerebrospinal fluid cells from patients with multiple sclerosis for detection of JC virus DNA.

@article{Iacobaeus2009AnalysisOC,
  title={Analysis of cerebrospinal fluid and cerebrospinal fluid cells from patients with multiple sclerosis for detection of JC virus DNA.},
  author={Ellen Iacobaeus and Caroline F. Ryschkewitsch and Maneth Gravell and Mohsen Khademi and Erik Wallstrom and Tomas Olsson and Lou Brundin and E O Major},
  journal={Multiple sclerosis},
  year={2009},
  volume={15 1},
  pages={28-35}
}
OBJECTIVE 1) To determine whether JC virus (JCV) DNA was present in the cerebrospinal fluid (CSF) and blood from patients with multiple sclerosis (MS) in comparison with controls and 2) to find out if our clinical material, based on presence of JCV DNA, included any patient at risk for progressive multifocal leukoencephalopathy (PML). METHODS The prevalence of JCV DNA was analyzed in CSF and plasma from 217 patients with MS, 86 patients with clinically isolated syndrome (CIS), and 212… CONTINUE READING

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