Analysis of cell-type-specific chromatin modifications and gene expression in Drosophila neurons that direct reproductive behavior

  title={Analysis of cell-type-specific chromatin modifications and gene expression in Drosophila neurons that direct reproductive behavior},
  author={Colleen M Palmateer and Shawn C Moseley and Surjyendu Ray and Savannah G. Brovero and Michelle N. Arbeitman},
  journal={PLoS Genetics},
Examining the role of chromatin modifications and gene expression in neurons is critical for understanding how the potential for behaviors are established and maintained. We investigate this question by examining Drosophila melanogaster fru P1 neurons that underlie reproductive behaviors in both sexes. We developed a method to purify cell-type-specific chromatin (Chromatag), using a tagged histone H2B variant that is expressed using the versatile Gal4/UAS gene expression system. Here, we use… 
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