Analysis of cell migration using the Dunn chemotaxis chamber and time-lapse microscopy.

@article{Wells2005AnalysisOC,
  title={Analysis of cell migration using the Dunn chemotaxis chamber and time-lapse microscopy.},
  author={Claire M. Wells and Anne J Ridley},
  journal={Methods in molecular biology},
  year={2005},
  volume={294},
  pages={31-41}
}
The directed migration of cells (chemotaxis) occurs not only during wound healing and inflammatory responses but also during embryonic development. However, the intracellular signaling pathways that enable a cell to detect a chemoattractant and subsequently migrate toward the source are not clearly defined. The Dunn chemotaxis chamber in conjunction with time-lapse microscopy is a powerful tool that enables the user to observe directly the morphological response of cells to a chemoattractant in… CONTINUE READING

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