Analysis of cell-based RNAi screens

  title={Analysis of cell-based RNAi screens},
  author={Michael Boutros and L{\'i}gia P Br{\'a}s and Wolfgang Huber},
  journal={Genome Biology},
  pages={R66 - R66}
RNA interference (RNAi) screening is a powerful technology for functional characterization of biological pathways. Interpretation of RNAi screens requires computational and statistical analysis techniques. We describe a method that integrates all steps to generate a scored phenotype list from raw data. It is implemented in an open-source Bioconductor/R package, cellHTS ( ). The method is useful for the analysis and documentation of individual RNAi screens… CONTINUE READING

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