Analysis of blood coagulation in mice: pre-analytical conditions and evaluation of a home-made assay for thrombin-antithrombin complexes

@article{Sommeijer2005AnalysisOB,
  title={Analysis of blood coagulation in mice: pre-analytical conditions and evaluation of a home-made assay for thrombin-antithrombin complexes},
  author={Dirkje W Sommeijer and Ren{\'e} van van Oerle and Pieter H. Reitsma and Janneke J Timmerman and Joost Meijers and Henri M H Spronk and Hugo Ten Cate},
  journal={Thrombosis Journal},
  year={2005},
  volume={3},
  pages={12 - 12}
}
BACKGROUND The use of mouse models for the study of thrombotic disorders has gained increasing importance. Methods for measurement of coagulation activation in mice are, however, scarce. The primary aim of this study was to develop a specific mouse thrombin-antithrombin (TAT) ELISA for measurement of coagulation activation and to compare it with two commercially available assays for human TAT complexes. In addition, we aimed to improve methods for mouse plasma anticoagulation and preparation… CONTINUE READING

From This Paper

Topics from this paper.

Citations

Publications citing this paper.
Showing 1-10 of 10 extracted citations

Effect of ambient particulate matter exposure on hemostasis.

Translational research : the journal of laboratory and clinical medicine • 2007
View 2 Excerpts

Hyperglycemia accelerates arterial thrombus formation and attenuates the antithrombotic response to endotoxin in mice.

Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis • 2007

References

Publications referenced by this paper.
Showing 1-10 of 11 references

The in vivo kinetics of tissue factor messenger RNA expression during human endotoxemia: relationship with activation of coagulation

RF Franco, E de Jonge, +9 authors PH Reitsma
Blood • 2000
View 1 Excerpt

Similar Papers

Loading similar papers…