Analysis of array CGH data for cancer studies using fused quantile regression

  title={Analysis of array CGH data for cancer studies using fused quantile regression},
  author={Youjuan Li and Ji Zhu},
  volume={23 18},
MOTIVATION The identification of DNA copy number changes provides insights that may advance our understanding of initiation and progression of cancer. Array-based comparative genomic hybridization (array-CGH) has emerged as a technique allowing high-throughput genome-wide scanning for chromosomal aberrations. A number of statistical methods have been proposed for the analysis of array-CGH data. In this article, we consider a fused quantile regression model based on three motivations: (1… CONTINUE READING
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