Analysis of apolipoprotein E, alpha1-antichymotrypsin and presenilin-1 genes polymorphisms in dementia caused by normal pressure hydrocephalus in man.

@article{Nacmias1997AnalysisOA,
  title={Analysis of apolipoprotein E, alpha1-antichymotrypsin and presenilin-1 genes polymorphisms in dementia caused by normal pressure hydrocephalus in man.},
  author={Benedetta Nacmias and Andrea Tedde and Bianca Maria Guarnieri and Concetta Petruzzi and L. Ortenzi and Antonio Serio and Luigi Amaducci and Sandro Sorbi},
  journal={Neuroscience letters},
  year={1997},
  volume={229 3},
  pages={177-80}
}
Normal pressure hydrocephalus (NPH) is characterized by dementia, gait disorders and urinary incontinence. Apolipoprotein E (ApoE) epsilon4 allele has been associated with severity of dementia in Alzheimer's disease (AD) and in other forms of dementia. Moreover, homozygosity of the A allele of the alpha1-antichymotrypsin (ACT) gene and of allele 1 of the… CONTINUE READING