Analysis of allele-specific gene expression using a target-oriented tiling microarray assay.

  title={Analysis of allele-specific gene expression using a target-oriented tiling microarray assay.},
  author={Huiyong Zhang and Xing Wang Deng and Lei Li},
  journal={Methods in molecular biology},
Advances in molecular and computational biology in recent years have led to the development or the improvement of methods for analyzing global gene expression. In most of these efforts, it is assumed that alleles of different origins contribute equally to the transcript pool. However, accumulating evidence suggests that many genes are not equally expressed from the paternal and maternal chromosomes. In addition to imprinting, the phenomenon of imbalanced allelic expression is widespread in… 



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