Analysis of accordion DNA stretching revealed by the gold cluster ruler.

@article{Mazur2009AnalysisOA,
  title={Analysis of accordion DNA stretching revealed by the gold cluster ruler.},
  author={Alexey K. Mazur},
  journal={Physical review. E, Statistical, nonlinear, and soft matter physics},
  year={2009},
  volume={80 1 Pt 1},
  pages={
          010901
        }
}
  • A. Mazur
  • Published 24 June 2009
  • Chemistry
  • Physical review. E, Statistical, nonlinear, and soft matter physics
A promising method for measuring intramolecular distances in solution uses small-angle x-ray scattering interference between gold nanocrystal labels [Mathew-Fenn, Science 322, 446 (2008)]. When applied to double-stranded DNA, it revealed that the DNA length fluctuations are strikingly strong and correlated over at least 80 base pair steps. In other words, the DNA behaves as accordion bellows with distant fragments stretching and shrinking concertedly. This hypothesis, however, disagrees with… 

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