Analysis of a large data set reveals haplotypes carrying putatively recessive lethal alleles with pleiotropic effects on economically important traits in beef cattle

@inproceedings{Jenko2018AnalysisOA,
  title={Analysis of a large data set reveals haplotypes carrying putatively recessive lethal alleles with pleiotropic effects on economically important traits in beef cattle},
  author={Janez Jenko and Matthew Charles McClure and Daragh Matthews and Jennifer Christine McClure and Martin Johnsson and Gregor Gorjanc and John M. Hickey},
  year={2018}
}
Background: Deleterious recessive alleles can result in reduced economic performance in livestock in multiple ways in homozygous individuals: from early embryonic death, death soon after birth, to being non-lethal but causing reduced viability. While death is an easy phenotype to score, reduced viability is not as easy to identify. However, it can sometimes be observed as reduced artificial insemination (AI) conception rates, longer calving intervals, or higher hazard for live born animals… CONTINUE READING