Analysis of a gene panel for targeted sequencing of colorectal cancer samples

@inproceedings{Jensen2018AnalysisOA,
  title={Analysis of a gene panel for targeted sequencing of colorectal cancer samples},
  author={Klaus H\ojgaard Jensen and Jose M G Izarzugaza and Agnieszka Sierakowska Juncker and Rasmus B Hansen and Torben Fr\ostrup Hansen and Pascal Timshel and Thorarinn Blondal and Thomas Sk\ot Jensen and Eske Rygaard-Hjalsted and Peter Mouritzen and Michael Thorsen and Rasmus Wernersson and Henrik Bj\orn Nielsen and Anders Kristian M Jakobsen and S\oren Brunak and Flemming Brandt S\orensen},
  booktitle={Oncotarget},
  year={2018}
}
Colorectal cancer (CRC) is a leading cause of death worldwide. Surgical intervention is a successful treatment for stage I patients, whereas other more advanced cases may require adjuvant chemotherapy. The selection of effective adjuvant treatments remains, however, challenging. Accurate patient stratification is necessary for the identification of the subset of patients likely responding to treatment, while sparing others from pernicious treatment. Targeted sequencing approaches may help in… CONTINUE READING