Analysis of TGM1, ALOX12B, ALOXE3, NIPAL4 and CYP4F22 in autosomal recessive congenital ichthyosis from Galicia (NW Spain): evidence of founder effects.

@article{RodrguezPazos2011AnalysisOT,
  title={Analysis of TGM1, ALOX12B, ALOXE3, NIPAL4 and CYP4F22 in autosomal recessive congenital ichthyosis from Galicia (NW Spain): evidence of founder effects.},
  author={Laura Rodr{\'i}guez-Pazos and Manuel Ginarte and Laura Fachal and Jaime Toribio and Angel Carracedo and Ana Mar{\'i}n Vega},
  journal={The British journal of dermatology},
  year={2011},
  volume={165 4},
  pages={906-11}
}
BACKGROUND   Mutations in six genes have been identified in autosomal recessive congenital ichthyosis (ARCI). To date, few studies have analysed the spectrum of these mutations in specific populations. OBJECTIVES We have studied the characteristics of patients with ARCI in Galicia (NW Spain). Methods  We recruited patients by contacting all dermatology… CONTINUE READING