Analysis of Serum Cholesterol Efflux Capacity in a Minipig Model of Nonischemic Heart Failure

@inproceedings{Bigazzi2017AnalysisOS,
  title={Analysis of Serum Cholesterol Efflux Capacity in a Minipig Model of Nonischemic Heart Failure},
  author={Federico Bigazzi and Maria Pia Adorni and Mariarita Puntoni and Francesco Sbrana and Vincenzo Lionetti and Beatrice Dal Pino and Elda Favari and Fabio A. Recchia and Franco Bernini and Tiziana Sampietro},
  booktitle={Journal of atherosclerosis and thrombosis},
  year={2017}
}
AIM Circulating levels of high-density lipoprotein cholesterol (HDL-C) are decreased in patients with heart failure (HF). We tested whether HDL-C serum levels are associated with cardiac contractile dysfunction in a minipig HF model. METHODS Blood samples were collected from 13 adult male minipigs: 1) before pacemaker implantation, 2) 10 days after surgery, and 3) 3 weeks after high-rate LV pacing. Serum cholesterol efflux capacity (CEC), an index of HDL functionality, was assessed through… CONTINUE READING

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