Analysis of Saccharomyces cerevisiae proteins induced by peroxide and superoxide stress.

@article{Jamieson1994AnalysisOS,
  title={Analysis of Saccharomyces cerevisiae proteins induced by peroxide and superoxide stress.},
  author={Derek J. Jamieson and Stuart L. Rivers and Duncan W S Stephen},
  journal={Microbiology},
  year={1994},
  volume={140 ( Pt 12)},
  pages={3277-83}
}
Exponentially growing Saccharomyces cerevisiae cells are more sensitive to oxidants such as hydrogen peroxide and superoxides than stationary phase cells. Using disruption mutations in the genes encoding the two S. cerevisiae superoxide dismutases, we show that the principal mechanism of toxicity of redox-cycling compounds, such as menadione and plumbagin, is via the production of superoxide anions. Using two-dimensional polyacrylamide gel electrophoresis we have compared the pattern of protein… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 38 extracted citations

Similar Papers

Loading similar papers…