Analysis of RNA Expression Profiles Identifies Dysregulated Vesicle Trafficking Pathways in Creutzfeldt-Jakob Disease

@article{BartolettiStella2018AnalysisOR,
  title={Analysis of RNA Expression Profiles Identifies Dysregulated Vesicle Trafficking Pathways in Creutzfeldt-Jakob Disease},
  author={Anna Bartoletti-Stella and Patrizia Corrado and Nicola Mometto and Simone Baiardi and Pascal F. Durrenberger and Thomas Arzberger and R Reynolds and Hans A. Kretzschmar and S Capellari and Piero Parchi},
  journal={Molecular Neurobiology},
  year={2018},
  pages={1-16}
}
Functional genomics applied to the study of RNA expression profiles identified several abnormal molecular processes in experimental prion disease. However, only a few similar studies have been carried out to date in a naturally occurring human prion disease. To better characterize the transcriptional cascades associated with sporadic Creutzfeldt-Jakob disease (sCJD), the most common human prion disease, we investigated the global gene expression profile in samples from the frontal cortex of 10… CONTINUE READING
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