Analysis of Plasma microRNA Associated with Hemolysis

Abstract

We analyzed the effect of hemolysis on microRNA profi le of blood plasma. It was found that hemolysis of ~0.05% erythrocytes in a sample signifi cantly affected the concentration of 9 microRNA: hsa-miR-486-5p, hsa-miR-16-5p, hsa-miR-451a, hsa-miR-106a-5p, hsa-miR-17-5p, hsa-miR-93-5p, hsa-miR-20a-5p, hsa-miR-107, and hsa-miR-20b-5p. The effect of hemolysis on plasma content of miR-17 family microRNA was demonstrated.

DOI: 10.1007/s10517-016-3300-y

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@article{Shkurnikov2016AnalysisOP, title={Analysis of Plasma microRNA Associated with Hemolysis}, author={M. Yu. Shkurnikov and E. N. Knyazev and K. A. Fomicheva and D. S. Mikhailenko and Kirill Mikhailovich Nyushko and E. K. Saribekyan and Timur R Samatov and B. Ya. Alekseev}, journal={Bulletin of Experimental Biology and Medicine}, year={2016}, volume={160}, pages={748-750} }