Analysis of P transposable element functions in Drosophila.

@article{Karess1984AnalysisOP,
  title={Analysis of P transposable element functions in Drosophila.},
  author={Roger E. Karess and Gerald M. Rubin},
  journal={Cell},
  year={1984},
  volume={38 1},
  pages={135-46}
}
We have made a P-element derivative called Pc[ry], which carries the selectable marker gene rosy, but which acts like a nondefective, intact P element. It transposes autonomously into the germline chromosomes of an M-strain Drosophila embryo and it mobilizes in trans the defective P elements of the singed-weak allele. Frameshift mutations introduced into any of the four major open reading frames of the P sequence were each sufficient to eliminate the transposase activity, but none affected… CONTINUE READING