Analysis of NPR-1 Reveals a Circuit Mechanism for Behavioral Quiescence in C. elegans

Abstract

Animals undergo periods of behavioral quiescence and arousal in response to environmental, circadian, or developmental cues. During larval molts, C. elegans undergoes a period of profound behavioral quiescence termed lethargus. Locomotion quiescence during lethargus was abolished in mutants lacking a neuropeptide receptor (NPR-1) and was reduced in mutants… (More)
DOI: 10.1016/j.neuron.2013.04.002

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