Analysis of N- and O-linked protein glycosylation in children with Prader-Willi syndrome.

@article{Munce2010AnalysisON,
  title={Analysis of N- and O-linked protein glycosylation in children with Prader-Willi syndrome.},
  author={Teresa Munce and Helen S. Heussler and Francis Gerard Bowling},
  journal={Journal of intellectual disability research : JIDR},
  year={2010},
  volume={54 10},
  pages={929-37}
}
BACKGROUND Current genotype-phenotype correlations in Prader-Willi syndrome (PWS) are struggling to give an explanation of the diversity in phenotype and there is a need to move towards a molecular understanding of PWS. A range of functions related to glycoproteins are involved in the pathophysiology of PWS and it may be that abnormal glycosylation is contributing to the biological phenotype. The objective of this study was to investigate the state of N- and O-linked glycosylation in children… CONTINUE READING

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