Analysis of N-acetyltransferase (NAT2) in three ethnic groups in Tunisia.

@article{Attitallah2000AnalysisON,
  title={Analysis of N-acetyltransferase (NAT2) in three ethnic groups in Tunisia.},
  author={S Attitallah and Y. C. Bechtel and Chelbi Belkahia and Pamela Bechtel},
  journal={Therapie},
  year={2000},
  volume={55 3},
  pages={361-9}
}
Acetylation status was compared, using caffeine as a probe drug, in the three main racial/ethnic groups living in Tunisia: Arabs, Berbers and Numides. The frequency of slow acetylators appears identical in these three groups and is different from that observed in Caucasians. However, the NAT-2 activity as a whole is lower in Tunisians than in Caucasians. These differences might be attributable to the various population mixings which occurred in the past, given the geographical position of… CONTINUE READING

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