Analysis of Mel-18 expression in prostate cancer tissues and correlation with clinicopathologic features.

@article{Wang2011AnalysisOM,
  title={Analysis of Mel-18 expression in prostate cancer tissues and correlation with clinicopathologic features.},
  author={Wei Wang and Tianxin Lin and Jian Huang and Weilie Hu and Kewei Xu and Jun Liu},
  journal={Urologic oncology},
  year={2011},
  volume={29 3},
  pages={244-51}
}
OBJECTIVE Mel-18 is a member of the polycomb group (PcG) of proteins, which are chromatin regulatory factors that play an important role in development and oncogenesis. This study was designed to investigate the clinical and prognostic significance of Mel-18 in the patients with prostate cancer. PATIENTS AND METHODS Immunostaining with Mel-18 specific antibodies was performed on paraffin sections from 202 patients. Correlations between Mel-18 and the Gleason grading system, clinical stage… CONTINUE READING