Analysis of Long-term Stored Plasma Samples for Investigation into the Pathophysiology of Vibration-induced White Finger: Preliminary Results

@inproceedings{KAWANO2014AnalysisOL,
  title={Analysis of Long-term Stored Plasma Samples for Investigation into the
Pathophysiology of Vibration-induced White Finger: Preliminary Results},
  author={Yoshinao KAWANO and Hossain Md. MAHBUB and Ryosuke Hase and T. Sakamoto and Noriaki Harada},
  booktitle={Industrial health},
  year={2014}
}
Blood samples were collected 25 yr ago from hand-arm vibration syndrome patients with vibration-induced white finge/VWF (VWF+ group) and without it (VWF- group), and healthy controls (n=12 in each group), and stored at -80 °C. The subjects provided venous blood twice: at baseline, and after cold exposure at 7 °C for 25 min. Blood specimens were analyzed for plasma endothelin-1 (ET-1) by an enzyme-linked immunosorbent assay. Baseline concentration of plasma ET-1 was found to be significantly… CONTINUE READING

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