Analysis of Kinetics of Dihydroethidium Fluorescence with Superoxide Using Xanthine Oxidase and Hypoxanthine Assay

@article{Chen2012AnalysisOK,
  title={Analysis of Kinetics of Dihydroethidium Fluorescence with Superoxide Using Xanthine Oxidase and Hypoxanthine Assay},
  author={Juan Chen and Steven C. Rogers and Mahendra Kavdia},
  journal={Annals of Biomedical Engineering},
  year={2012},
  volume={41},
  pages={327-337}
}
Superoxide (O2 −) is an important reactive oxygen species (ROS), and has an essential role in physiology and pathophysiology. An accurate detection of O2 − is needed to better understand numerous vascular pathologies. In this study, we performed a mechanistic study by using the xanthine oxidase (XOD)/hypoxanthine (HX) assay for O2 − generation and a O2… CONTINUE READING