Analysis of IL-1α, IL-1β, and IL-RA polymorphisms in dysthymia

  title={Analysis of IL-1α, IL-1β, and IL-RA polymorphisms in dysthymia},
  author={Sofia M. M. Fertuzinhos and Jo{\~a}o Ricardo M. Oliveira and Agnes Lumi Nishimura and Deyse Pontual and Daniel Rocha Carvalho and Everton Botelho Sougey and Paulo A Otto and Mayana Zatz},
  journal={Journal of Molecular Neuroscience},
Investigators of independent studies reported alterations in cytokine serum levels in patients with different mood disorders. Several polymorphisms associated with neuropsychiatric disorders such as schizophrenia and Alzheimer’s disease have been reported at the interleukin-1 (IL-1) panel. Here we report the results of three specific polymorphisms at the IL-1α, IL-1β, and IL-1RA genes, which were analyzed in 128 Brazilian subjects: 59 dysthymic patients and 69 normal controls. We found a… CONTINUE READING