Analysis of Her2/neu membrane protein clusters in different types of breast cancer cells using localization microscopy

  title={Analysis of Her2/neu membrane protein clusters in different types of breast cancer cells using localization microscopy},
  author={Ren{\'e} Kaufmann and P. Mueller and G. Hildenbrand and M. Hausmann and C. Cremer},
  journal={Journal of Microscopy},
  • René Kaufmann, P. Mueller, +2 authors C. Cremer
  • Published 2011
  • Biology, Medicine
  • Journal of Microscopy
  • The Her2/neu tyrosine kinase receptor is a member of the epidermal growth factor family. It plays an important role in tumour genesis of certain types of breast cancer and its overexpression correlates with distinct diagnostic and therapeutic decisions. Nevertheless, it is still under intense investigation to improve diagnostic outcome and therapy control. In this content, we applied spectral precision distance/position determination microscopy, a technique based on the general principles of… CONTINUE READING
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