Analysis of HLA-DM polymorphism in juvenile dermatomyositis (JDM) patients.

  title={Analysis of HLA-DM polymorphism in juvenile dermatomyositis (JDM) patients.},
  author={Justin E. West and Ann M. Reed},
  journal={Human immunology},
  volume={60 3},
Annually approximately 1:200,000 young children and adolescents are affected by juvenile dermatomyositis (JDM). Genetic factors are thought to contribute to the etiology. Since the discovery of the human leukocyte antigen class II associated DM molecule much has been learned about its role in the normal processing of HLA-class II molecules with a limited number of polymorphisms being found. Blood samples were collected from 30 patients who were seen in the clinic and 40 healthy volunteers. Exon… CONTINUE READING