Analysis of Genomic G + C Content, Codon Usage, Initiator Codon Context and Translation Termination Sites In Tetrahymena Thermophila

@article{Wuitschick1999AnalysisOG,
  title={Analysis of Genomic G + C Content, Codon Usage, Initiator Codon Context and Translation Termination Sites In Tetrahymena Thermophila},
  author={Jeffrey D. Wuitschick and K. M. Karrer},
  journal={Journal of Eukaryotic Microbiology},
  year={1999},
  volume={46}
}
ABSTRACT. In recent years, the amount of molecular sequencing data from Tetrahymena thermophila has dramatically increased. We analyzed G + C content, codon usage, initiator codon context and stop codon sites in the extremely A + T rich genome of this ciliate. Average G + C content was 38% for protein coding regions. 21% for 5′ non‐coding sequences, 19% for 3′ non‐coding sequences, 15% for introns, 19% for micronuclear limited sequences and 17% for macronuclear retained sequences flanking… 
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The first demonstration of a serine/threonine kinase enzyme in the unicellular eukaryotic protozoan T. thermophila is demonstrated, showing to be phosphorylated in threonine and tyrosine.
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A better understanding of viral palindromic densities and GC-ratios would help in understanding conserved secondary RNA structures in viral genomes and future drug discovery and to determine evolutionary traits in genomes.
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