Analysis of Fifty Hotspot Mutations of Lung Squamous Cell Carcinoma in Never-smokers

@inproceedings{Lee2017AnalysisOF,
  title={Analysis of Fifty Hotspot Mutations of Lung Squamous Cell Carcinoma in Never-smokers},
  author={Ha Youn Lee and Se Hoon Lee and Jae Kyung Won and Dong Soo Lee and Nak Jung Kwon and Sun Mi Choi and Jin Woo Lee and Chang Hoon Lee and Sang Min Lee and Jae Joon Yim and Chul Gyu Yoo and Young Whan Kim and Sung Koo Han and Young Sik Park},
  booktitle={Journal of Korean medical science},
  year={2017}
}
Smoking is the major risk factor for lung squamous cell carcinoma (SCC), although a small number of lung SCCs occurs in never-smokers. The purpose of this study was to compare 50 hotspot mutations of lung SCCs between never-smokers and smokers. We retrospectively reviewed the medical records of patients newly diagnosed with lung SCC between January 1, 2011 and December 31, 2013 in the Seoul National University Hospital. Formalin-fixed, paraffin-embedded tumor samples were used for analysis of… CONTINUE READING