Analysis of EEG–fMRI data in focal epilepsy based on automated spike classification and Signal Space Projection

  title={Analysis of EEG–fMRI data in focal epilepsy based on automated spike classification and Signal Space Projection},
  author={Adam D. Liston and Jan C. de Munck and Khalid Hamandi and Helmut Laufs and Pauly P. W. Ossenblok and John S. Duncan and Louis Lemieux},

Localizing Epileptic Foci Using Simultaneous EEG-fMRI Recording: Template Component Cross-Correlation

The proposed method goes beyond the conventional methods by breaking the dependency on spikes and using the outside-the-scanner spike templates and the selected components, achieving an accuracy of 97%.

EEG–fMRI in Adults with Focal Epilepsy

EEG–fMRI is free of critical assumptions and may therefore give a more accurate indication of the source or sources of IEDs, which may reflect propagated activity rather than the source.

The combination of EEG Source Imaging and EEG‐correlated functional MRI to map epileptic networks

A description of the neurophysiologic mechanisms that give rise to the measured signals is described, followed by validation studies based on comparison with intracranial EEG and surgical outcome, and analysis strategies to combine both techniques are discussed.



Combining EEG and fMRI in Epilepsy: Methodological Challenges and Clinical Results

  • J. GotmanC. BénarF. Dubeau
  • Medicine
    Journal of clinical neurophysiology : official publication of the American Electroencephalographic Society
  • 2004
This article reviews the experience with this method in more than 100 studies performed over the last 4 years at the Montreal Neurological Institute, and gives examples of fMRI responses seen with focal spikes and with generalized spike and wave discharges.

Spatio-temporal imaging of focal interictal epileptiform activity using EEG-triggered functional MRI.

EEG-triggered, blood oxygen level-dependent functional MRI (BOLD-fMRI) was used in 24 patients with localization-related epilepsy and frequent interictal epileptiform discharges (spikes) to identify

Comparison of Spike-Triggered Functional MRI BOLD Activation and EEG Dipole Model Localization

The degree of agreement between the BOLD and EEG source localization indicates that the combination of these two noninvasive techniques offers the possibility of advancing the study of the generators of epileptiform electrical activity.

EEG/Functional MRI in Epilepsy: The Queen Square Experience

The issues in recording EEG during fMRI are addressed and the application of EEG/fMRI in the study of patients with epilepsy at the centre is reviewed.

Event-Related fMRI with Simultaneous and Continuous EEG: Description of the Method and Initial Case Report

A new technique for the simultaneous and continuous acquisition of functional MRI data and EEG recording on a patient with epilepsy and localization of the BOLD activation associated with the EEG events was consistent with previous findings and EEG source modeling.