Analysis of DNA-binding activity of the JC virus minor capsid protein VP2

Abstract

To investigate the DNA binding activity of the JC virus minor capsid protein, VP2, both wild-type and mutant VP2 were cloned and expressed in Escherichia coli. Southwestern blotting was employed for the DNA-binding assay. The results showed that VP2 was able to bind to DNA, except when either the last 13 or the last 29 amino acids were truncated. The… (More)
DOI: 10.1080/13550280390195289

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