Analysis of DNA-Protein Interactions in Complexes of Transcription Factor NF-κB with DNA

Abstract

We have applied bioinformatic analysis of X-ray 3D structures of complexes of transcription factor NF-κB with DNAs. We determined the number of possible Van der Waals contacts and hydrogen bonds between amino acid residues and nucleotides. Conservative contacts in the NF-κB dimer-DNA complex composed of p50 and/or p65 NF-κB subunit and DNA sequences like 5… (More)
DOI: 10.1007/s10541-005-0249-2

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