Analysis of CD44 interactions with hyaluronan in murine L cell fibroblasts deficient in glycosaminoglycan synthesis: a role for chondroitin sulfate.

@article{Esford1998AnalysisOC,
  title={Analysis of CD44 interactions with hyaluronan in murine L cell fibroblasts deficient in glycosaminoglycan synthesis: a role for chondroitin sulfate.},
  author={Lesley Esford and Arpita Maiti and Sharon A Bader and Frank Tufaro and Pauline Johnson},
  journal={Journal of cell science},
  year={1998},
  volume={111 ( Pt 7)},
  pages={1021-9}
}
CD44 is a widely expressed cell adhesion molecule that binds the extracellular matrix component, hyaluronan, in a tightly regulated manner. Previous studies have shown that the CD44-hyaluronan interaction is affected by changes in the glycosylation state of CD44. In this study, we take advantage of several well-characterized murine L cell mutants defective… CONTINUE READING