Analysis of CD161 expression on human CD8+ T cells defines a distinct functional subset with tissue-homing properties.

@article{Billerbeck2010AnalysisOC,
  title={Analysis of CD161 expression on human CD8+ T cells defines a distinct functional subset with tissue-homing properties.},
  author={Eva Billerbeck and Yu-Hoi Kang and Lucy S K Walker and Helen Lockstone and Stefanie Grafmueller and Vicki Maria Fleming and Jonathan Flint and Chris B Willberg and Bertram Bengsch and Bianca Seigel and Narayan Ramamurthy and Nicole Zitzmann and Eleanor J. Barnes and Jonarthan T H Thevanayagam and Anisha Bhagwanani and Alasdair Leslie and Ye Htun Oo and Simon D Kollnberger and Paul Bowness and Oliver Drognitz and David H Adams and H. E. Blum and Robert Thimme and Paul Klenerman},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={2010},
  volume={107 7},
  pages={
          3006-11
        }
}
CD8(+) T lymphocytes play a key role in host defense, in particular against important persistent viruses, although the critical functional properties of such cells in tissue are not fully defined. We have previously observed that CD8(+) T cells specific for tissue-localized viruses such as hepatitis C virus express high levels of the C-type lectin CD161. To explore the significance of this, we examined CD8(+)CD161(+) T cells in healthy donors and those with hepatitis C virus and defined a… CONTINUE READING

Citations

Publications citing this paper.
SHOWING 1-10 OF 138 CITATIONS

CXCR3-dependent recruitment and CCR6-mediated positioning of Th-17 cells in the inflamed liver

  • Journal of hepatology
  • 2012
VIEW 8 EXCERPTS
CITES BACKGROUND
HIGHLY INFLUENCED

Enhanced Th1/Th17 Functions of CD161+ CD8+ T Cells in Mucosal Tissues of Rhesus Macaques

  • PloS one
  • 2016
VIEW 11 EXCERPTS
CITES BACKGROUND & RESULTS
HIGHLY INFLUENCED

Functional role of mucosal-associated invariant T cells in HIV infection.

  • Journal of leukocyte biology
  • 2016
VIEW 10 EXCERPTS
CITES BACKGROUND & RESULTS
HIGHLY INFLUENCED

FILTER CITATIONS BY YEAR

2010
2018

CITATION STATISTICS

  • 24 Highly Influenced Citations

  • Averaged 17 Citations per year over the last 3 years

  • 55% Increase in citations per year in 2018 over 2017

References

Publications referenced by this paper.
SHOWING 1-10 OF 51 REFERENCES

Similar Papers

Loading similar papers…