Analysis of CCR5Δ32 Geographic Distribution and Its Correlation with Some Climatic and Geographic Factors

@article{Limborska2002AnalysisOC,
  title={Analysis of CCR5$\Delta$32 Geographic Distribution and Its Correlation with Some Climatic and Geographic Factors},
  author={S. Limborska and O. Balanovsky and E. V. Balanovskaya and P. Slominsky and Maria I Schadrina and L. Livshits and S. Kravchenko and Vladimir M Pampuha and E. Khusnutdinova and V. Spitsyn},
  journal={Human Heredity},
  year={2002},
  volume={53},
  pages={49 - 54}
}
We studied the possible effects of climatic-geographic factors on the world distribution of the mutant allele for the chemokine receptor gene CCR5, which has a 32-bp deletion (CCR5Δ32) preventing cell invasion by the primary transmitting strain of HIV-1. New data on CCR5 polymorphisms in Russian, Ukrainian, and Moldavian populations are presented. All available data on CCR5Δ32 frequencies in the Old World (number of populations n = 77) were used for construction of a geographical gene map to… Expand
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  • E. Faure, Manuela Royer-Carenzi
  • Biology, Medicine
  • Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases
  • 2008
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References

SHOWING 1-10 OF 41 REFERENCES
Dating the origin of the CCR5-Delta32 AIDS-resistance allele by the coalescence of haplotypes.
Mountains and genes: population history of the Pyrenees.
Clines of nuclear DNA markers suggest a largely neolithic ancestry of the European gene pool.
...
1
2
3
4
5
...