Analysis of Biological Networks: Networks in Disease

Abstract

Figure 1 depicts the construction of the diseasome bipartite network: (Center) A small subset of OMIMbased disorder disease gene associations, where circles and rectangles correspond to disorders and disease genes, respectively. A link is placed between a disorder and a disease gene if mutations in that gene lead to the specific disorder. The size of a circle is proportional to the number of genes participating in the corresponding disorder, and the color corresponds to the disorder class to which the disease belongs. (Left) The HDN projection of the diseasome bipartite graph, in which two disorders are connected if there is a gene that is implicated in both. The width of a link is proportional to the number of genes that are implicated in

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Cite this paper

@inproceedings{Sharan2009AnalysisOB, title={Analysis of Biological Networks: Networks in Disease}, author={Roded Sharan and Naama Hazan}, year={2009} }