Analysis of Biodistribution and Engraftment into the Liver of Genetically Modified Mesenchymal Stromal Cells Derived from Adipose Tissue

  title={Analysis of Biodistribution and Engraftment into the Liver of Genetically Modified Mesenchymal Stromal Cells Derived from Adipose Tissue},
  author={Giuliana Di Rocco and Antonietta Gentile and Annalisa Antonini and Silvia Truffa and Giulia Piaggio and Maurizio Colognesi Capogrossi and Gabriele Toietta},
  journal={Cell Transplantation},
  pages={1997 - 2008}
Presently, orthotopic liver transplant is the major therapeutic option for patients affected by primary liver diseases. This procedure is characterized by major invasive surgery, scarcity of donor organs, high costs, and lifelong immunosuppressive treatment. Transplant of hepatic precursor cells represents an attractive alternative. These cells could be used either for allogeneic transplantation or for autologous transplant after ex vivo genetic modification. We used stromal cells isolated from… 

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