Analysis of BRCA1 and BRCA2 mutations in Brazilian breast cancer patients with positive family history.

@article{Dufloth2005AnalysisOB,
  title={Analysis of BRCA1 and BRCA2 mutations in Brazilian breast cancer patients with positive family history.},
  author={Rozany Mucha Dufloth and S{\'i}lvia H Carvalho and Juliana Karina Ruiz Heinrich and J{\'u}lia Yoriko Shinzato and C{\'e}sar Cabello dos Santos and Luiz Carlos Zeferino and Fernando de Lander Schmitt},
  journal={Sao Paulo medical journal = Revista paulista de medicina},
  year={2005},
  volume={123 4},
  pages={192-7}
}
CONTEXT AND OBJECTIVE BRCA1 and BRCA2 are the two principal hereditary breast cancer susceptibility genes, and the prevalence of their mutations among Brazilian women is unknown. The objective was to detect BRCA1 and BRCA2 mutations in Brazilian patients with breast cancer, so as to establish genetic profiles. DESIGN AND SETTING Cross-sectional study, in Centro de Atenção Integral à Saúde da Mulher, Universidade Estadual de Campinas, Brazil, and Institute of Pathology and Molecular Immunology… CONTINUE READING
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