Analysis of BRAFV600E mutation and DNA methylation improves the diagnostics of thyroid fine needle aspiration biopsies

Abstract

BACKGROUND Thyroid nodules with indeterminate cytological features on fine needle aspiration biopsy specimens (FNABs) have a ~20% risk of thyroid cancer. BRAF(V600E) mutation and DNA methylation are useful markers to distinguish malignant thyroid neoplasm from benign. The aim of this study was to determine whether combined detection of BRAF(V600E) mutation… (More)
DOI: 10.1186/1746-1596-9-45

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@inproceedings{Zhang2014AnalysisOB, title={Analysis of BRAFV600E mutation and DNA methylation improves the diagnostics of thyroid fine needle aspiration biopsies}, author={Bingfei Zhang and Shu Liu and Zhaoxia Zhang and Jing Wei and Yiping Qu and Kexia Wu and Qi Fan Yang and Peng Hou and Bingyin Shi}, booktitle={Diagnostic pathology}, year={2014} }