Analysis of Adult Neurogenesis: Evidence for a Prominent “Non-Neurogenic” DCX-Protein Pool in Rodent Brain

@inproceedings{Kremer2013AnalysisOA,
  title={Analysis of Adult Neurogenesis: Evidence for a Prominent “Non-Neurogenic” DCX-Protein Pool in Rodent Brain},
  author={Thomas Dipl.-Ing. Kremer and Ravi Jagasia and Annika Herrmann and Hugues Matile and Edilio Borroni and Fiona Francis and Hans Georg Kuhn and Christian Czech},
  booktitle={PloS one},
  year={2013}
}
Here, we have developed a highly sensitive immunoassay for Dcx to characterize expression in brain and cerebrospinal fluid (CSF) of rodents. We demonstrate that Dcx is widely expressed during development in various brain regions and as well can be detected in cerebrospinal fluid of rats (up to 30 days postnatal). While Dcx protein level decline in adulthood and were detectable in neurogenic regions of the adult rodent brain, similar levels were also detectable in brain regions expected to bear… CONTINUE READING
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