Analysis of 388 cases of primary sclerosing cholangitis in Japan; Presence of a subgroup without pancreatic involvement in older patients.

@article{Takikawa2004AnalysisO3,
  title={Analysis of 388 cases of primary sclerosing cholangitis in Japan; Presence of a subgroup without pancreatic involvement in older patients.},
  author={Hajime Takikawa and Yoriyuki Takamori and Atsushi Tanaka and Hiroko Kurihara and Yasuni Nakanuma},
  journal={Hepatology research : the official journal of the Japan Society of Hepatology},
  year={2004},
  volume={29 3},
  pages={153-159}
}
We analyzed 388 cases of primary sclerosing cholangitis (PSC) in Japan, according to a questionnaire sent to gastroenterologists. There was male predominance (59%), and interestingly there were two peaks in the age distribution as seen in the previous study. Jaundice and itching, major symptoms in PSC patients included in the diagnostic criteria, were observed only 28 and 16%, respectively. Alkaline phosphatase level was less than twofold of the upper limit of the normal range in 35%. In this… CONTINUE READING